Chicago - Kenya's Brigid Kosgei shattered Paula Radcliffe's 16-year-old women's marathon world record on Sunday, winning the Chicago Marathon in two hours, 14 minutes and four seconds.
She crossed the finish line alone, with Ethiopians Ababel Yeshaneh and Gelete Burka a distant second and third in 2:20:51 and 2:20:55.
Kosgei signalled her intentions with an astonishing first five kilometres in 15:28 - so far inside Radcliffe's world record pace that it seemed she might have ruined her chances out of the gate.
The pace-setters dropped away in the closing kilometres, leaving Kosgei to break the tape alone, her arms raised in celebration.
"I ran here last year so I knew it was a good course. There was a little bit of wind but it was OK.
Last year's winner Mo Farah of Britain was never a factor - finishing a distant eighth in 2:09:58.
Karoki settled for fourth in 2:05:53.
Salazar has denied wrongdoing, but Nike shut down its Oregon Project running group headed by Salazar, and four-time Olympic gold medalist Farah arrived in Chicago for his defence to find himself again denying any irregularities during his time with the coach.
1. Lawrence Cherono (KEN) 2hr 05min 45sec
4. Bedan Karoki (KEN) 2:05:53
7. Dickson Chumba (KEN) 2:09:11
10. Jerrell Mock (USA) 2:10:37
2. Ababel Yeshaneh (ETH) 2:20:51
5. Fionnuala McCormack (IRL) 2:26:47
8. Laura Thweatt (USA) 2:29:06